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Gene Review:

hemE - uroporphyrinogen decarboxylase

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Xu, K. et al., Desrochers, M. et al.

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Disease relevance of hemE

Mapping of the hemE locus in Salmonella typhimurium [1].
To study the post-uroporphyrin steps in heme and chlorophyll biosynthesis in Chlorobium, we attempted to clone the uroporphyrinogen decarboxylase ( hemE) gene [2].

High impact information on hemE

The recombinant DNA molecules were transduced into an auxotrophic Salmonella double mutant ( hemA(-) hemE(-)) by phage P22 [2].

References

Mapping of the hemE locus in Salmonella typhimurium. Desrochers, M., Peloquin, L., Săsărman, A. J. Bacteriol. (1978) [Pubmed]
Cloning and expression of Chlorobium vibrioforme uroporphyrinogen decarboxylase gene in a Salmonella heme auxotroph. Xu, K., Ndivo, V., Majumdar, D. Curr. Microbiol. (2002) [Pubmed]

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