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Gene Review:

merT - mercuric transport protein

Shigella flexneri 2b

Philippidis, G.P. et al., Jobling, M.G. et al., Gambill, B.D. et al.

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High impact information on merT

These data suggested that early after induction only 20% of the transcripts initiating at merT proceed beyond merC [1].
The results indicated that, with increasing gene copy number, there was an approximately 5-fold increase in the merA gene product compared with a 2.5-fold increase in the merT gene product [2].
Each mercury resistance clone synthesized polypeptides equivalent in size to the merA, merT, and merP gene products [3].

Biological context of merT

RNA hybridizations indicated that mRNA of the cytoplasmic mercuric reductase (merA gene product) increased 11-fold with the 47-fold gene amplification, while mRNA of the transport protein (merT gene product) increased only 5.4-fold [2].

References

Synthesis and degradation of the mRNA of the Tn21 mer operon. Gambill, B.D., Summers, A.O. J. Mol. Biol. (1992) [Pubmed]
Effect of gene amplification on mercuric ion reduction activity of Escherichia coli. Philippidis, G.P., Malmberg, L.H., Hu, W.S., Schottel, J.L. Appl. Environ. Microbiol. (1991) [Pubmed]
Restriction pattern and polypeptide homology among plasmid-borne mercury resistance determinants. Jobling, M.G., Peters, S.E., Ritchie, D.A. Plasmid (1988) [Pubmed]

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