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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

LRRC25  -  leucine rich repeat containing 25

Homo sapiens

Synonyms: FLJ38116, Leucine-rich repeat-containing protein 25, MAPA, Monocyte and plasmacytoid-activated protein, UNQ6169/PRO20174
 
 
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Disease relevance of LRRC25

  • All patients received megavoltage external beam radiotherapy (RT) in daily fractions of 1.8-2.0 Gy, five times a week, to a median total dose of 50 Gy and an initial hyperthermia treatment (HT) of I h duration utilizing the BSD 2000 with Sigma 60 or MAPA applicators at frequencies of 60-140 MHz [1].
 

Analytical, diagnostic and therapeutic context of LRRC25

  • Two Monoclonal Antibodies produced against Pancreatic Amylase have been produced and used to develop immunoassays (MAPA assays) for serum isoamylases [2].
  • The remaining four sections cover general concepts, evaluation schemes, and treatment procedures of four practitioners belonging to different schools of thought in orthopedic manual therapy: James Cyriax, MD, MRCP; Freddy Kaltenborn, DO, RPT; Geoffrey Maitland, MAPA, FCSP; and John McM Mennell, MD [3].

References

  1. A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy. Maguire, P.D., Samulski, T.V., Prosnitz, L.R., Jones, E.L., Rosner, G.L., Powers, B., Layfield, L.W., Brizel, D.M., Scully, S.P., Harrelson, J.M., Dewhirst, M.W. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. (2001) [Pubmed]
  2. Direct, rapid assay of pancreatic isoamylase activity by use of monoclonal antibodies with low affinity for macroamylasemic complexes. Rosenblum, J.L. Clin. Chem. (1988) [Pubmed]
  3. Orthopedic manual therapy--an overview. Part I: the extremities. Cookson, J.C., Kent, B.E. Physical therapy. (1979) [Pubmed]
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