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Gene Review: 

Crry-ps  -  complement receptor related protein,...

Mus musculus

Synonyms: Crrx, Mcp-ps, mCRX
 
 
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High impact information on Crry-ps

  • The coding sequences of the Crry gene encompass over 25 kb of DNA, whereas the Crry-ps sequences are included within a single 5.6-kb Eco-R1 fragment [1].
  • DNA sequence analysis of the Crry-ps gene indicates that this sequence most likely represents a pseudogene resulting from a processed mRNA transcript from the Crry gene [1].
  • This conclusion is based on the lack of intervening sequences in the Crry-ps gene and the observation that the Crry-ps gene sequence contains both an 11-bp deletion within the "coding" region and a degenerate poly A tail at the 3' end of the homologous sequence [1].
 

Biological context of Crry-ps

  • These genes, termed murine CRY (mCRY) and murine CRX (mCRX) reside on murine chromosomes 1 and 8, respectively [2].

References

  1. The murine complement receptor gene family. III. The genomic and transcriptional complexity of the Crry and Crry-ps genes. Paul, M.S., Aegerter, M., Cepek, K., Miller, M.D., Weis, J.H. J. Immunol. (1990) [Pubmed]
  2. The murine complement receptor gene family. Analysis of mCRY gene products and their homology to human CR1. Paul, M.S., Aegerter, M., O'Brien, S.E., Kurtz, C.B., Weis, J.H. J. Immunol. (1989) [Pubmed]
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