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Gene Review

VPS37A  -  vacuolar protein sorting 37 homolog A (S....

Homo sapiens

Synonyms: ESCRT-I complex subunit VPS37A, FLJ32642, HCRP1, Hepatocellular carcinoma-related protein 1, PQBP2, ...
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Disease relevance of VPS37A

  • At baseline correlations between inflammatory markers and age, anthropometry, body composition and the metabolic parameters were non-significant; only positive associations were found between tumour necrosis factor alpha and body weight (r = 0.617, p = 0.033) and between HCRP and BMI (r = 0.594, p = 0.041) [1].
  • Three genes (FLJ32642, MTSG1, and PCM1) had a significantly (P< 0.001, P< 0.004, and P< 0.001) lower expression in primary ovarian carcinoma compared with controls (ovarian tissues and cysts) [2].


  1. Inflammatory markers in adults with Prader-Willi syndrome before and during 12 months growth hormone treatment. Höybye, C. Horm. Res. (2006) [Pubmed]
  2. Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival. Pils, D., Horak, P., Gleiss, A., Sax, C., Fabjani, G., Moebus, V.J., Zielinski, C., Reinthaller, A., Zeillinger, R., Krainer, M. Cancer (2005) [Pubmed]
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