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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Body Composition

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Disease relevance of Body Composition


Psychiatry related information on Body Composition


High impact information on Body Composition


Chemical compound and disease context of Body Composition


Biological context of Body Composition


Anatomical context of Body Composition


Associations of Body Composition with chemical compounds

  • Sequence of changes in body composition induced by testosterone and reversal of changes after drug is stopped [31].
  • The benefit of this was probably counteracted by an increased metabolic rate, since reversal of plasma levels of T3 and free T4 had no net effect on body composition of freely eating sarcoma-bearing mice, although it had a negative effect on body and muscle composition in food-restricted controls [32].
  • To investigate whether these perturbations have metabolic consequences, we compared the effects of 24 wk each of oral (Premarin 1.25 mg) and transdermal (Estraderm 100TTS) estrogen on energy metabolism and body composition in 18 postmenopausal women in an open-label randomized crossover study [33].
  • The aim of this study was to investigate the relationship of serum leptin to gender, body composition, and tumor necrosis factor (TNF) [34].
  • In six patients, body composition was studied prior to lithium carbonate therapy, after 17 days of treatment, and 17 days after discontinuing administration of the drug [35].

Gene context of Body Composition


Analytical, diagnostic and therapeutic context of Body Composition


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  2. Body cell mass and leucine metabolism in cirrhosis. McCullough, A.J., Mullen, K.D., Kalhan, S.C. Gastroenterology (1992) [Pubmed]
  3. Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis. DiFedele, L.M., He, J., Bonkowski, E.L., Han, X., Held, M.A., Bohan, A., Menon, R.K., Denson, L.A. Gastroenterology (2005) [Pubmed]
  4. Beneficial effects of adenosine triphosphate on nutritional status in advanced lung cancer patients: a randomized clinical trial. Agteresch, H.J., Rietveld, T., Kerkhofs, L.G., van den Berg, J.W., Wilson, J.H., Dagnelie, P.C. J. Clin. Oncol. (2002) [Pubmed]
  5. Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion. Fan, W., Yanase, T., Nomura, M., Okabe, T., Goto, K., Sato, T., Kawano, H., Kato, S., Nawata, H. Diabetes (2005) [Pubmed]
  6. Severe decrements in cognition function and mood induced by sleep loss, heat, dehydration, and undernutrition during simulated combat. Lieberman, H.R., Bathalon, G.P., Falco, C.M., Kramer, F.M., Morgan, C.A., Niro, P. Biol. Psychiatry (2005) [Pubmed]
  7. Hormonal and body composition predictors of soluble leptin receptor, leptin, and free leptin index in adolescent girls with anorexia nervosa and controls and relation to insulin sensitivity. Misra, M., Miller, K.K., Almazan, C., Ramaswamy, K., Aggarwal, A., Herzog, D.B., Neubauer, G., Breu, J., Klibanski, A. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
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  10. Paradoxical sleep deprivation and sleep recovery: effects on the hypothalamic-pituitary-adrenal axis activity, energy balance and body composition of rats. Hipólide, D.C., Suchecki, D., Pimentel de Carvalho Pinto, A., Chiconelli Faria, E., Tufik, S., Luz, J. J. Neuroendocrinol. (2006) [Pubmed]
  11. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Fleury, C., Neverova, M., Collins, S., Raimbault, S., Champigny, O., Levi-Meyrueis, C., Bouillaud, F., Seldin, M.F., Surwit, R.S., Ricquier, D., Warden, C.H. Nat. Genet. (1997) [Pubmed]
  12. Estrogen regulation of growth hormone action. Leung, K.C., Johannsson, G., Leong, G.M., Ho, K.K. Endocr. Rev. (2004) [Pubmed]
  13. Human pituitary growth hormone (hGH) therapy in growth hormone deficiency. Frasier, S.D. Endocr. Rev. (1983) [Pubmed]
  14. Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. LeBoff, M.S., Kohlmeier, L., Hurwitz, S., Franklin, J., Wright, J., Glowacki, J. JAMA (1999) [Pubmed]
  15. Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes. de Luca, C., Kowalski, T.J., Zhang, Y., Elmquist, J.K., Lee, C., Kilimann, M.W., Ludwig, T., Liu, S.M., Chua, S.C. J. Clin. Invest. (2005) [Pubmed]
  16. The metabolic effects of lopinavir/ritonavir in HIV-negative men. Lee, G.A., Seneviratne, T., Noor, M.A., Lo, J.C., Schwarz, J.M., Aweeka, F.T., Mulligan, K., Schambelan, M., Grunfeld, C. AIDS (2004) [Pubmed]
  17. Energy balance in asymptomatic HIV infection. Sharpstone, D.R., Murray, C.P., Ross, H.M., Hancock, M.R., Phelan, M.S., Crane, R.C., Menzies, I.S., Reaveley, D.A., Lepri, A.C., Nelson, M.R., Gazzard, B.G. AIDS (1996) [Pubmed]
  18. Energy expenditure and body composition in children with Crohn's disease: effect of enteral nutrition and treatment with prednisolone. Azcue, M., Rashid, M., Griffiths, A., Pencharz, P.B. Gut (1997) [Pubmed]
  19. Effects of testosterone replacement in androgen-deficient women with hypopituitarism: a randomized, double-blind, placebo-controlled study. Miller, K.K., Biller, B.M., Beauregard, C., Lipman, J.G., Jones, J., Schoenfeld, D., Sherman, J.C., Swearingen, B., Loeffler, J., Klibanski, A. J. Clin. Endocrinol. Metab. (2006) [Pubmed]
  20. Twenty-four-hour energy balance in Crohn disease patients: metabolic implications of steroid treatment. Mingrone, G., Benedetti, G., Capristo, E., De Gaetano, A., Greco, A.V., Tataranni, P.A., Gasbarrini, G. Am. J. Clin. Nutr. (1998) [Pubmed]
  21. Nutritional status in the neuroendocrine control of growth hormone secretion: the model of anorexia nervosa. Scacchi, M., Ida Pincelli, A., Cavagnini, F. Frontiers in neuroendocrinology. (2003) [Pubmed]
  22. Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters. Maher, B., Lloyd, J., Wilkins, E.G., Fraser, W.D., Back, D., Park, B.K., Pirmohamed, M. Antivir. Ther. (Lond.) (2004) [Pubmed]
  23. The androgen receptor mRNA. Yeap, B.B., Wilce, J.A., Leedman, P.J. Bioessays (2004) [Pubmed]
  24. Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice. Blüher, S., Moschos, S., Bullen, J., Kokkotou, E., Maratos-Flier, E., Wiegand, S.J., Sleeman, M.W., Sleemann, M.W., Mantzoros, C.S. Diabetes (2004) [Pubmed]
  25. Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring. Franks, P.W., Looker, H.C., Kobes, S., Touger, L., Tataranni, P.A., Hanson, R.L., Knowler, W.C. Diabetes (2006) [Pubmed]
  26. Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. Masaki, T., Chiba, S., Yasuda, T., Noguchi, H., Kakuma, T., Watanabe, T., Sakata, T., Yoshimatsu, H. Diabetes (2004) [Pubmed]
  27. Pharmacokinetics in the elderly. Studies on ciprofloxacin. Lebel, M., Bergeron, M.G. Am. J. Med. (1987) [Pubmed]
  28. HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study. Carr, A., Hudson, J., Chuah, J., Mallal, S., Law, M., Hoy, J., Doong, N., French, M., Smith, D., Cooper, D.A. AIDS (2001) [Pubmed]
  29. The effect of hormone replacement therapy on body composition, body fat distribution, and insulin sensitivity in menopausal women: a randomized, double-blind, placebo-controlled trial. Sites, C.K., L'Hommedieu, G.D., Toth, M.J., Brochu, M., Cooper, B.C., Fairhurst, P.A. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  30. Effect of protein source on resistive-training-induced changes in body composition and muscle size in older men. Haub, M.D., Wells, A.M., Tarnopolsky, M.A., Campbell, W.W. Am. J. Clin. Nutr. (2002) [Pubmed]
  31. Sequence of changes in body composition induced by testosterone and reversal of changes after drug is stopped. Forbes, G.B., Porta, C.R., Herr, B.E., Griggs, R.C. JAMA (1992) [Pubmed]
  32. Thyroid hormones and experimental cancer cachexia. Svaninger, G., Lundberg, P.A., Lundholm, K. J. Natl. Cancer Inst. (1986) [Pubmed]
  33. The route of estrogen replacement therapy confers divergent effects on substrate oxidation and body composition in postmenopausal women. O'Sullivan, A.J., Crampton, L.J., Freund, J., Ho, K.K. J. Clin. Invest. (1998) [Pubmed]
  34. Gender-dependent alterations in serum leptin in alcoholic cirrhosis. McCullough, A.J., Bugianesi, E., Marchesini, G., Kalhan, S.C. Gastroenterology (1998) [Pubmed]
  35. Body composition in affective disorder before, during, and after lithium carbonate therapy. Colt, E.W., Dunner, D.L., Wang, J., Ross, D.C., Pierson, R.N., Fieve, R.R. Arch. Gen. Psychiatry (1982) [Pubmed]
  36. Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice. Chen, N.G., Swick, A.G., Romsos, D.R. J. Clin. Invest. (1997) [Pubmed]
  37. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Sun, Y., Wang, P., Zheng, H., Smith, R.G. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  38. Genome-wide search for loci controlling serum IGF binding protein levels of mice. Brockmann, G.A., Haley, C.S., Wolf, E., Karle, S., Kratzsch, J., Renne, U., Schwerin, M., Hoeflich, A. FASEB J. (2001) [Pubmed]
  39. Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes. Pihlajamäki, J., Kinnunen, M., Ruotsalainen, E., Salmenniemi, U., Vauhkonen, I., Kuulasmaa, T., Kainulainen, S., Laakso, M. Diabetologia (2005) [Pubmed]
  40. Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. Lillioja, S., Mott, D.M., Spraul, M., Ferraro, R., Foley, J.E., Ravussin, E., Knowler, W.C., Bennett, P.H., Bogardus, C. N. Engl. J. Med. (1993) [Pubmed]
  41. Nutritional aspects of body water dislocations in postoperative and depleted patients. Elwyn, D.H., Bryan-Brown, C.W., Shoemaker, W.C. Ann. Surg. (1975) [Pubmed]
  42. Circulating IL-18 concentration is associated with insulin sensitivity and glucose tolerance through increased fat-free mass. Bosch, M., Lopez-Bermejo, A., Vendrell, J., Musri, M., Ricart, W., Fernandez-Real, J.M. Diabetologia (2005) [Pubmed]
  43. Metabolic effects of indinavir in healthy HIV-seronegative men. Noor, M.A., Lo, J.C., Mulligan, K., Schwarz, J.M., Halvorsen, R.A., Schambelan, M., Grunfeld, C. AIDS (2001) [Pubmed]
  44. Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone. Vandenput, L., Boonen, S., Van Herck, E., Swinnen, J.V., Bouillon, R., Vanderschueren, D. J. Bone Miner. Res. (2002) [Pubmed]
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