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Gene Review

Gart  -  phosphoribosylglycinamide formyltransferase

Mus musculus

Synonyms: Gaps, Prgs, Trifunctional purine biosynthetic protein adenosine-3
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High impact information on Gart

  • The glycinamide ribonucleotide formyltransferase gene, Gart, is encoded 5' of Son in a head-to-head arrangement, with the start of both genes lying within 899 bp [1].
  • DESIGN: Gaps were produced in the zona pellucida of mouse oocytes or two-cell embryos by zona drilling with acid Tyrode's solution [2].


  1. Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes. Wynn, S.L., Fisher, R.A., Pagel, C., Price, M., Liu, Q.Y., Khan, I.M., Zammit, P., Dadrah, K., Mazrani, W., Kessling, A., Lee, J.S., Buluwela, L. Genomics (2000) [Pubmed]
  2. An intact zona pellucida is not necessary for successful mouse embryo cryopreservation. Garrisi, G.J., Talansky, B.E., Sapira, V., Gordon, J.W., Navot, D. Fertil. Steril. (1992) [Pubmed]
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