Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

ST13P4 - suppression of tumorigenicity 13 (colon...

Homo sapiens

Synonyms: FAM10A4, FAM10A4P, Suppression of tumorigenicity 13 pseudogene 4

Sossey-Alaoui, K. et al., van Everdink, W.J. et al.

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Disease relevance of FAM10A4

Using the 650-kb DNA sequence from the minimally deleted region in B-cell chronic lymphocytic leukemia (BCLL), we have identified a new gene, FAM10A4, that maps to the proximal end of the region [1].
Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer [1].

High impact information on FAM10A4

RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia [2].

Biological context of FAM10A4

We conclude that RFP2, c13ORF1, and a chromosome 13-specific ST13-like gene, FAM10A4, are the most likely candidates for such a type of B-CLL TSG [2].

References

Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer. Sossey-Alaoui, K., Kitamura, E., Head, K., Cowell, J.K. Genomics (2002) [Pubmed]
RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia. van Everdink, W.J., Baranova, A., Lummen, C., Tyazhelova, T., Looman, M.W., Ivanov, D., Verlind, E., Pestova, A., Faber, H., van der Veen, A.Y., Yankovsky, N., Vellenga, E., Buys, C.H. Cancer Genet. Cytogenet. (2003) [Pubmed]

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