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Gene Review

NCAN  -  neurocan

Homo sapiens

Synonyms: CSPG3, Chondroitin sulfate proteoglycan 3, NEUR, Neurocan core protein
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Disease relevance of NCAN


High impact information on NCAN

  • Children > or = 3 at diagnosis: 20 of 30 patients completed pre-CSI CH without progression; 15 are alive NED at 1.3-9.2 years, and 5 showed post-CSI progression in the PF (n = 3), in the NEUR (n = 1) and in bone marrow (n = 1) [2].


  1. Lysosomal high molecular weight multienzyme complex. Ostrowska, H., Krukowska, K., Kalinowska, J., Orłowska, M., Lengiewicz, I. Cell. Mol. Biol. Lett. (2003) [Pubmed]
  2. Patterns of failure in children with medulloblastoma: effects of preirradiation chemotherapy. Hartsell, W.F., Gajjar, A., Heideman, R.L., Langston, J.A., Sanford, R.A., Walter, A., Jones, D., Chen, G., Kun, L.E. Int. J. Radiat. Oncol. Biol. Phys. (1997) [Pubmed]
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