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Gene Review

APCDD1  -  adenomatosis polyposis coli down-regulated 1

Homo sapiens

Synonyms: Adenomatosis polyposis coli down-regulated 1 protein, B7323, DRAPC1, FP7019, HHS, ...
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Disease relevance of APCDD1

  • Moreover, we documented elevated expression of APCDD1 in 18 of 27 primary colon cancer tissues compared with corresponding noncancerous mucosae [1].

High impact information on APCDD1


  1. Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. Takahashi, M., Fujita, M., Furukawa, Y., Hamamoto, R., Shimokawa, T., Miwa, N., Ogawa, M., Nakamura, Y. Cancer Res. (2002) [Pubmed]
  2. Drapc1 expression during mouse embryonic development. Jukkola, T., Sinjushina, N., Partanen, J. Gene Expr. Patterns (2004) [Pubmed]
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