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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

FAM163A  -  family with sequence similarity 163, member A

Homo sapiens

Synonyms: C1orf76, Cebelin, MGC16664, NDSP, Neuroblastoma-derived secretory protein, ...
 
 
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Disease relevance of C1orf76

  • Recently, neuroblastoma-derived secretory protein (NDSP) was identified and cloned from neuroblastoma [1].
  • We also found that bone marrow samples with known tumor infiltration had much higher NDSP mRNA levels than bone marrow from patients without metastasis [1].
 

High impact information on C1orf76

  • CONCLUSION: From these data, we conclude that NDSP mRNA levels in neuroblastoma tumor tissue correlate with risk group assignment and may serve as a marker for metastasis in bone marrow [1].
 

Analytical, diagnostic and therapeutic context of C1orf76

  • METHODS: Using quantitative real-time PCR, we tested NDSP messenger RNA (mRNA) expression in 45 neuroblastoma tumor samples and 5 bone marrow samples [1].

References

  1. Neuroblastoma-derived secretory protein messenger RNA levels correlate with high-risk neuroblastoma. Vasudevan, S.A., Russell, H.V., Okcu, M.F., Burlingame, S.M., Liu, Z.J., Yang, J., Nuchtern, J.G. J. Pediatr. Surg. (2007) [Pubmed]
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