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Gene Review

PARP15  -  poly (ADP-ribose) polymerase family,...

Homo sapiens

Synonyms: ADP-ribosyltransferase diphtheria toxin-like 7, ARTD7, B-aggressive lymphoma protein 3, BAL3, FLJ40597, ...
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High impact information on PARP15

  • In addition, we show that BAL2 and BAL3, but not BAL1, exhibit PARP activity [1].
  • NO2+allergen enhanced the percentage of neutrophils in both BW and BAL compared to air+allergen (BW 19 vs. 11, P=0.05; BAL 3 vs. 1, P=0.02 median values).The levels of eosinophil cationic protein (ECP) in BW was higher after NO2+allergen compared to air+allergen (90 vs. 3.6 microg/l; P=0.02, median values) [2].


  1. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity. Aguiar, R.C., Takeyama, K., He, C., Kreinbrink, K., Shipp, M.A. J. Biol. Chem. (2005) [Pubmed]
  2. Ambient level of NO2 augments the inflammatory response to inhaled allergen in asthmatics. Barck, C., Sandström, T., Lundahl, J., Halldén, G., Svartengren, M., Strand, V., Rak, S., Bylin, G. Respiratory medicine. (2002) [Pubmed]
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