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Gene Review

Recql5  -  RecQ protein-like 5

Mus musculus

Synonyms: ATP-dependent DNA helicase Q5, DNA helicase, RecQ-like type 5, RECQL5beta, RecQ5, Recq5b, ...
 
 
 
 
 
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High impact information on Recql5

  • Thus, this study identifies a previously unknown Recql5-dependent, Blm-independent pathway for suppressing crossovers during mitosis in mice [1].
  • Furthermore, we show that mouse embryonic fibroblasts derived from Recql5 knockout mice also exhibit a significantly increased frequency of SCE compared with the corresponding wild-type control [1].

References

  1. Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Hu, Y., Lu, X., Barnes, E., Yan, M., Lou, H., Luo, G. Mol. Cell. Biol. (2005) [Pubmed]
 
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