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Gene Review

PDIA3P1  -  protein disulfide isomerase family A,...

Homo sapiens

Synonyms: ERp60, GRP58P, PDIA3P
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High impact information on PDIA3P

  • Chondrocytes produce 1alpha,25(OH)(2)D(3) (10(-8)M), which binds ERp60, activating PLA(2), and resulting lysophospholipids lead to MV membrane disorganization, releasing active MMPs [1].
  • Like plasma membranes (PM), MVs contain the 1alpha,25(OH)(2)D(3)-binding protein ERp60, phospholipase A(2) (PLA(2)), and caveolin-1, but appear to lack nuclear Vitamin D receptors (VDRs) [1].


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