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Gene Review

Grip2  -  glutamate receptor interacting protein 2

Rattus norvegicus

Synonyms: AMPA receptor-interacting protein GRIP2, GRIP-2, Glutamate receptor-interacting protein 2
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High impact information on Grip2

  • Like GRIP (which we now term GRIP1), ABP-L/GRIP2 contains a seventh PDZ domain at its C terminus [1].
  • GRIP1 and GRIP2 are widely expressed in brain, with the highest levels found in the cerebral cortex, hippocampus, and olfactory bulb [2].


  1. Association of AMPA receptors with a subset of glutamate receptor-interacting protein in vivo. Wyszynski, M., Valtschanoff, J.G., Naisbitt, S., Dunah, A.W., Kim, E., Standaert, D.G., Weinberg, R., Sheng, M. J. Neurosci. (1999) [Pubmed]
  2. Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2. Dong, H., Zhang, P., Song, I., Petralia, R.S., Liao, D., Huganir, R.L. J. Neurosci. (1999) [Pubmed]
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