Gene Review:
cps-6 - Protein CPS-6
Caenorhabditis elegans
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Analytical, diagnostic and therapeutic context of cps-6
- Reduction of cps-6 activity caused by a genetic mutation or RNA-mediated interference (RNAi) affects normal DNA degradation, as revealed by increased staining in a TUNEL assay, and results in delayed appearance of cell corpses during development in C. elegans [1].
References
- Mitochondrial endonuclease G is important for apoptosis in C. elegans. Parrish, J., Li, L., Klotz, K., Ledwich, D., Wang, X., Xue, D. Nature (2001) [Pubmed]
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