Gene Review:
dad-1 - Protein DAD-1
Caenorhabditis elegans
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High impact information on dad-1
- dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates [1].
Biological context of dad-1
- Extra surviving cells were present in these animals, indicating that both the human and C.elegans dad-1 genes can suppress developmentally programmed cell death [1].
Anatomical context of dad-1
- The dad-1 gene, which encodes a novel 113 amino acid protein, was originally identified in a mutant hamster cell line (tsBN7) that undergoes apoptosis at restrictive temperature [1].
References
- dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates. Sugimoto, A., Hozak, R.R., Nakashima, T., Nishimoto, T., Rothman, J.H. EMBO J. (1995) [Pubmed]
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