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Gene Review

che-3  -  Protein CHE-3

Caenorhabditis elegans

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High impact information on che-3

  • To test the hypothesis that the minus end-directed microtubule motor protein, cytoplasmic dynein, drives this retrograde transport pathway, we visualized movement of kinesin-II and its cargo along dendrites and cilia in a che-3 cytoplasmic dynein mutant background, and observed an inhibition of retrograde transport in cilia but not in dendrites [1].
  • E1033 (che-2) and E1124 (che-3) cause defects in the ciliary structure of all but one type of ciliated sensory neuron in the head [2].


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