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Gene Review:

pad-1 - Protein PAD-1

Caenorhabditis elegans

Guipponi, M. et al.

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High impact information on pad-1

C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning [1].
Most of the tissues of the embryo failed to undergo proper patterning during gastrulation, and morphogenesis did not occur; thus we termed the ortholog pad-1, for patterning defective 1 [1].

References

C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning. Guipponi, M., Brunschwig, K., Chamoun, Z., Scott, H.S., Shibuya, K., Kudoh, J., Delezoide, A.L., El Samadi, S., Chettouh, Z., Rossier, C., Shimizu, N., Mueller, F., Delabar, J.M., Antonarakis, S.E. Genomics (2000) [Pubmed]

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