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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

syd-1  -  Protein SYD-1

Caenorhabditis elegans

 
 
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High impact information on syd-1

  • We now show that in syd-1 and syd-2 mutants, synaptic vesicles and numerous other presynaptic proteins fail to accumulate at presynaptic sites [1].
  • We show here that loss-of-function mutations in the C. elegans gene syd-1 cause presynaptic specializations to form in the dendritic processes of GABA-expressing motor neurons during initial differentiation [2].

References

  1. Hierarchical assembly of presynaptic components in defined C. elegans synapses. Patel, M.R., Lehrman, E.K., Poon, V.Y., Crump, J.G., Zhen, M., Bargmann, C.I., Shen, K. Nat. Neurosci. (2006) [Pubmed]
  2. SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP-like domains, specifies axon identity in C. elegans. Hallam, S.J., Goncharov, A., McEwen, J., Baran, R., Jin, Y. Nat. Neurosci. (2002) [Pubmed]
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