Chemical Compound Review:
Aminalon 4-aminobutanoic acid
Synonyms:
Gammalon, Aminalone, GABA, Aminobutyric acid, Aminobutyric Acids, ...
- Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure. Basile, A.S., Hughes, R.D., Harrison, P.M., Murata, Y., Pannell, L., Jones, E.A., Williams, R., Skolnick, P. N. Engl. J. Med. (1991)
- Deficiency of the beta 3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice. Culiat, C.T., Stubbs, L.J., Woychik, R.P., Russell, L.B., Johnson, D.K., Rinchik, E.M. Nat. Genet. (1995)
- Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus. Solimena, M., Folli, F., Denis-Donini, S., Comi, G.C., Pozza, G., De Camilli, P., Vicari, A.M. N. Engl. J. Med. (1988)
- Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase. Hogema, B.M., Gupta, M., Senephansiri, H., Burlingame, T.G., Taylor, M., Jakobs, C., Schutgens, R.B., Froestl, W., Snead, O.C., Diaz-Arrastia, R., Bottiglieri, T., Grompe, M., Gibson, K.M. Nat. Genet. (2001)
- Intrathecal baclofen for severe spinal spasticity. Penn, R.D., Savoy, S.M., Corcos, D., Latash, M., Gottlieb, G., Parke, B., Kroin, J.S. N. Engl. J. Med. (1989)
- Brain GABA levels in asymptomatic Huntington's disease. Reynolds, G.P., Pearson, S.J. N. Engl. J. Med. (1990)
- Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Horike, S., Cai, S., Miyano, M., Cheng, J.F., Kohwi-Shigematsu, T. Nat. Genet. (2005)
- Inhibitory threshold for critical-period activation in primary visual cortex. Fagiolini, M., Hensch, T.K. Nature (2000)
- Seizure protection and increased nerve-terminal GABA: delayed effects of GABA transaminase inhibition. Gale, K., Iadarola, M.J. Science (1980)
- Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders. Mignot, E., Taheri, S., Nishino, S. Nat. Neurosci. (2002)
- Cell and receptor type-specific alterations in markers of GABA neurotransmission in the prefrontal cortex of subjects with schizophrenia. Lewis, D.A., Hashimoto, T., Morris, H.M. Neurotox. Res (2008)
- Molecular structure and physiological function of chloride channels. Jentsch, T.J., Stein, V., Weinreich, F., Zdebik, A.A. Physiol. Rev. (2002)
- Molecular biology of mammalian plasma membrane amino acid transporters. Palacín, M., Estévez, R., Bertran, J., Zorzano, A. Physiol. Rev. (1998)
- Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Graf, E.R., Zhang, X., Jin, S.X., Linhoff, M.W., Craig, A.M. Cell (2004)
- Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy. Cossette, P., Liu, L., Brisebois, K., Dong, H., Lortie, A., Vanasse, M., Saint-Hilaire, J.M., Carmant, L., Verner, A., Lu, W.Y., Wang, Y.T., Rouleau, G.A. Nat. Genet. (2002)
- Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Kitamura, K., Yanazawa, M., Sugiyama, N., Miura, H., Iizuka-Kogo, A., Kusaka, M., Omichi, K., Suzuki, R., Kato-Fukui, Y., Kamiirisa, K., Matsuo, M., Kamijo, S., Kasahara, M., Yoshioka, H., Ogata, T., Fukuda, T., Kondo, I., Kato, M., Dobyns, W.B., Yokoyama, M., Morohashi, K. Nat. Genet. (2002)
- GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels. Holz, G.G., Rane, S.G., Dunlap, K. Nature (1986)
- Postsynaptic fall in intracellular pH induced by GABA-activated bicarbonate conductance. Kaila, K., Voipio, J. Nature (1987)
- GABA receptors in clonal cell lines: a model for study of benzodiazepine action at molecular level. Baraldi, M., Guidotti, A., Schwartz, J.P., Costa, E. Science (1979)
- Substantia nigra: site of anticonvulsant activity mediated by gamma-aminobutyric acid. Iadarola, M.J., Gale, K. Science (1982)
- Experimental hepatic encephalopathy: changes in the binding of gamma-aminobutyric acid. Baraldi, M., Zeneroli, Z.L. Science (1982)
- Co-localization of GABA receptors and benzodiazepine receptors in the brain shown by monoclonal antibodies. Schoch, P., Richards, J.G., Häring, P., Takacs, B., Stähli, C., Staehelin, T., Haefely, W., Möhler, H. Nature (1985)
- How opioids inhibit GABA-mediated neurotransmission. Vaughan, C.W., Ingram, S.L., Connor, M.A., Christie, M.J. Nature (1997)
- Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Cowley, M.A., Smart, J.L., Rubinstein, M., Cerdán, M.G., Diano, S., Horvath, T.L., Cone, R.D., Low, M.J. Nature (2001)
- Identification and characterization of the vesicular GABA transporter. McIntire, S.L., Reimer, R.J., Schuske, K., Edwards, R.H., Jorgensen, E.M. Nature (1997)
- Modulation of GABAA receptors by tyrosine phosphorylation. Moss, S.J., Gorrie, G.H., Amato, A., Smart, T.G. Nature (1995)
- First genetic evidence of GABA(A) receptor dysfunction in epilepsy: a mutation in the gamma2-subunit gene. Baulac, S., Huberfeld, G., Gourfinkel-An, I., Mitropoulou, G., Beranger, A., Prud'homme, J.F., Baulac, M., Brice, A., Bruzzone, R., LeGuern, E. Nat. Genet. (2001)
- Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome. Solimena, M., Folli, F., Aparisi, R., Pozza, G., De Camilli, P. N. Engl. J. Med. (1990)
- Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA. Hamill, O.P., Bormann, J., Sakmann, B. Nature (1983)
- The role of GABA in the substantia nigra. James, T.A., Starr, M.S. Nature (1978)
- Imaging of radiocarbon-labelled tracer molecules in neural tissue using accelerator mass spectrometry. Hedges, R.E., Jiang, Z.X., Ramsey, C.B., Cowey, A., Roberts, J.D., Somogyi, P. Nature (1996)
- Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Watanabe, D., Inokawa, H., Hashimoto, K., Suzuki, N., Kano, M., Shigemoto, R., Hirano, T., Toyama, K., Kaneko, S., Yokoi, M., Moriyoshi, K., Suzuki, M., Kobayashi, K., Nagatsu, T., Kreitman, R.J., Pastan, I., Nakanishi, S. Cell (1998)
- G-protein modulation of ion permeation through N-type calcium channels. Kuo, C.C., Bean, B.P. Nature (1993)
- Chronic blockade of dopamine receptors by antischizophrenic drugs enhances GABA binding in substantia nigra. Gale, K. Nature (1980)
- Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Labarca, C., Nowak, M.W., Zhang, H., Tang, L., Deshpande, P., Lester, H.A. Nature (1995)
- Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution. LaSalle, J.M., Lalande, M. Nat. Genet. (1995)
- Genes required for GABA function in Caenorhabditis elegans. McIntire, S.L., Jorgensen, E., Horvitz, H.R. Nature (1993)
- Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Costa, R.M., Federov, N.B., Kogan, J.H., Murphy, G.G., Stern, J., Ohno, M., Kucherlapati, R., Jacks, T., Silva, A.J. Nature (2002)
- Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein. Jin, Y., Hoskins, R., Horvitz, H.R. Nature (1994)
- GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Chattopadhyaya, B., Di Cristo, G., Wu, C.Z., Knott, G., Kuhlman, S., Fu, Y., Palmiter, R.D., Huang, Z.J. Neuron (2007)
- The Arabidopsis her1 mutant implicates GABA in E-2-hexenal responsiveness. Mirabella, R., Rauwerda, H., Struys, E.A., Jakobs, C., Triantaphylidès, C., Haring, M.A., Schuurink, R.C. Plant J. (2008)
- Identification of GABA in human CSF by gas liquid chromatography and mass spectrometry. Huizinga, J.D., Teelken, A.W., Muskiet, F.A., vd Meulen, J., Wolthers, B.G. N. Engl. J. Med. (1977)
- Cortical magnification factor and the ganglion cell density of the primate retina. Wässle, H., Grünert, U., Röhrenbeck, J., Boycott, B.B. Nature (1989)
- Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures. Choh, D.W., Farb, D.H., Fischbach, G.D. Nature (1977)
- Denervation supersensitivity in the striatonigral GABA pathway. Waddington, J.L., Cross, A.J. Nature (1978)
- Identification of sleep-promoting neurons in vitro. Gallopin, T., Fort, P., Eggermann, E., Cauli, B., Luppi, P.H., Rossier, J., Audinat, E., Mühlethaler, M., Serafin, M. Nature (2000)