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Gene Review

uaf-1  -  Protein UAF-1

Caenorhabditis elegans

 
 
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High impact information on uaf-1

  • It is composed of six exons, including an alternatively spliced third exon interrupting the gene at the same location as in C. elegans. uaf-1 is contained in an operon with the rab-18 gene in both species [1].
  • In the most abundant class the open reading frame is similar to that for the U2AF65 from mammals and flies [1].
  • We demonstrate by RNA interference that both U2AF genes, uaf-1 (which encodes U2AF65) and uaf-2, are required for viability, whereas cyp-13 is apparently not [2].

References

 
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