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Gene Review

pps-1  -  Protein PPS-1

Caenorhabditis elegans

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High impact information on pps-1

  • PPS-1 protein exhibits specific activity to form PAPS in vitro, and disruption of the pps-1 gene by RNAi causes pleiotropic developmental defects in muscle patterning and epithelial cell shape changes with a decrease in glycosaminoglycan sulfation [1].


  1. Essential Roles of 3'-Phosphoadenosine 5'-Phoshosulfate Synthase in Embryonic and Larval Development of the Nematode Caenorhabditis elegans. Dejima, K., Seko, A., Yamashita, K., Gengyo-Ando, K., Mitani, S., Izumikawa, T., Kitagawa, H., Sugahara, K., Mizuguchi, S., Nomura, K. J. Biol. Chem. (2006) [Pubmed]
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