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Gene Review

hsp-1  -  Protein HSP-1

Caenorhabditis elegans

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High impact information on hsp-1

  • The transgene, driven by the Pt hsp-1 promoter, was constitutively expressed in intestinal cells at all stages of both parasitic and free-living life cycles, although gene silencing appears to occur in some transgenic progeny [1].
  • Sequence data reveal that the hsp-2ps gene is a pseudogene of the constitutively expressed, heat-inducible hsp-1 gene [2].
  • The hsp-2ps gene duplicates a region of the hsp-1 gene that lies exclusively within the transcribed region and retains the introns [2].


  1. Heritable transgenesis of Parastrongyloides trichosuri: a nematode parasite of mammals. Grant, W.N., Skinner, S.J., Newton-Howes, J., Grant, K., Shuttleworth, G., Heath, D.D., Shoemaker, C.B. Int. J. Parasitol. (2006) [Pubmed]
  2. Identification of a heat-shock pseudogene from Caenorhabditis elegans. Heschl, M.F., Baillie, D.L. Genome (1989) [Pubmed]
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