Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

fox-1 - Protein FOX-1

Caenorhabditis elegans

Skipper, M. et al., Hodgkin, J. et al., Nicoll, M. et al., Kiehl, T.R. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on fox-1

The other uses the putative RNA-binding protein encoded by fox-1 to reduce the level of xol-1 protein [1].
Identification of a candidate primary sex determination locus, fox-1, on the X chromosome of Caenorhabditis elegans [2].
fox-1 was previously identified as a candidate numerator element based on its overexpression phenotype [3].
In order to elucidate the function of atx-2 and fox-1, we conducted RNA interference (RNAi) studies [4].

Other interactions of fox-1

Additionally, fox-1(Delta) impairs male mating efficiency, which, we propose, represents another function of fox-1, independent of xol-1 and its role in sex determination [3].

References

X-chromosome-counting mechanisms that determine nematode sex. Nicoll, M., Akerib, C.C., Meyer, B.J. Nature (1997) [Pubmed]
Identification of a candidate primary sex determination locus, fox-1, on the X chromosome of Caenorhabditis elegans. Hodgkin, J., Zellan, J.D., Albertson, D.G. Development (1994) [Pubmed]
Genetic and molecular analysis of fox-1, a numerator element involved in Caenorhabditis elegans primary sex determination. Skipper, M., Milne, C.A., Hodgkin, J. Genetics (1999) [Pubmed]
The ortholog of human ataxin-2 is essential for early embryonic patterning in C. elegans. Kiehl, T.R., Shibata, H., Pulst, S.M. J. Mol. Neurosci. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.