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Gene Review

ser-7  -  Protein SER-7

Caenorhabditis elegans

 
 
 
 
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High impact information on ser-7

  • Interestingly, 5-HT inhibits egg laying and pharyngeal pumping in ser-7 null mutants and the 5-HT inhibition of egg laying, but not pumping, is abolished in ser-7(tm1325);ser-4(ok512) double mutants [1].
  • 5-HT also fails to stimulate egg laying in ser-7(tm1325), ser-1(ok345), and ser-7(tm1325) ser-1(ok345) animals, but only the ser-7 ser-1 double mutants exhibit an Egl phenotype [1].

References

  1. SER-7, a Caenorhabditis elegans 5-HT7-like receptor, is essential for the 5-HT stimulation of pharyngeal pumping and egg laying. Hobson, R.J., Hapiak, V.M., Xiao, H., Buehrer, K.L., Komuniecki, P.R., Komuniecki, R.W. Genetics (2006) [Pubmed]
 
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