Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Nos1ap - nitric oxide synthase 1 (neuronal) adaptor...

Rattus norvegicus

Synonyms: C-terminal PDZ ligand of neuronal nitric oxide synthase protein, Capon, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, Nitric oxide synthase 1 adaptor protein

Sánchez-Islas, E. et al., Che, Y.H. et al., Tochio, H. et al.

Che, Tamatani, Tohyama,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Capon

The interaction of the PSD-95 PDZ2 with a carboxyl-terminal peptide derived from a cytoplasmic protein CAPON was studied by NMR titration experiments [1].
Neural nitric oxide synthase (nNOS), synapsin I, and nNOS adapter protein (CAPON) constitute a ternary complex necessary for specific NO and synapsin functions at a presynaptic level [2].

Analytical, diagnostic and therapeutic context of Capon

Signals of mRNA for PSD-95 and CAPON were initially expressed in the facial motoneurons, transiently decreased following axotomy and gradually recovered to the control level [3].

References

Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95. Tochio, H., Hung, F., Li, M., Bredt, D.S., Zhang, M. J. Mol. Biol. (2000) [Pubmed]
Nitric oxide synthase inhibition during synaptic maturation decreases synapsin I immunoreactivity in rat brain. Sánchez-Islas, E., León-Olea, M. Nitric Oxide (2004) [Pubmed]
Changes in mRNA for post-synaptic density-95 (PSD-95) and carboxy-terminal PDZ ligand of neuronal nitric oxide synthase following facial nerve transection. Che, Y.H., Tamatani, M., Tohyama, M. Brain Res. Mol. Brain Res. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg