The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia
  • UniProt
  • Ensembl

Table of contents

About

Terms

 

Gene Review: 

Mrpl23  -  mitochondrial ribosomal protein L23

Mus musculus

Synonyms: 39S ribosomal protein L23, mitochondrial, L23 mitochondrial-related protein, L23mrp, L23mt, MRP-L23, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Mrpl23

  • It is therefore suggested that the intergenic region between H19 and L23mrp contains a boundary or an insulator element [1].
  • Analysis of mice with a targeted deletion of the enhancers demonstrated that they were not disrupted in the expression of L23mrp [2].
  • We have cloned and characterized its mouse homolog, L23mrp, which maps to the conserved syntenic region on mouse chromosome 7 [2].
  • The promoter of L23mrp is a CpG island that is transcribed ubiquitously, but at different levels, in different fetal tissues [2].
 

Other interactions of Mrpl23

  • We find a transition from asynchronous replication at the imprinted mouse H19 gene to synchronous replication at the downstream Rpl23 gene, the human homologue of which appears to be non-imprinted [3].

References

  1. An evolutionarily conserved putative insulator element near the 3' boundary of the imprinted Igf2/H19 domain. Ishihara, K., Sasaki, H. Hum. Mol. Genet. (2002) [Pubmed]
  2. Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers. Zubair, M., Hilton, K., Saam, J.R., Surani, M.A., Tilghman, S.M., Sasaki, H. Genomics (1997) [Pubmed]
  3. The mouse H19 locus mediates a transition between imprinted and non-imprinted DNA replication patterns. Greally, J.M., Starr, D.J., Hwang, S., Song, L., Jaarola, M., Zemel, S. Hum. Mol. Genet. (1998) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities