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Gene Review

APLF  -  aprataxin and PNKP like factor

Homo sapiens

Synonyms: APFL, Aprataxin and PNK-like factor, Apurinic-apyrimidinic endonuclease APLF, C2orf13, MGC47799, ...
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Physical interactions of APLF

  • Yeast two-hybrid analyses suggest that APLF also interacts with the double-strand break repair proteins XRCC4 and XRCC5 (Ku86) [1].

Other interactions of APLF


  1. APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks. Iles, N., Rulten, S., El-Khamisy, S.F., Caldecott, K.W. Mol. Cell. Biol. (2007) [Pubmed]
  2. Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks. Bekker-Jensen, S., Fugger, K., Danielsen, J.R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, J., Mailand, N. J. Biol. Chem. (2007) [Pubmed]
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