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Gene Review

Tra2b  -  transformer 2 beta homolog (Drosophila)

Mus musculus

Synonyms: 5730405G21Rik, D16Ertd266e, SIG-41, Sfrs10, Silg41, ...
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Disease relevance of Sfrs10


High impact information on Sfrs10

  • Northern analysis and RT-PCR assays showed that SIG41 mRNA is present in virtually all the cell lines and tissues studied, with remarkable levels of expression in uterus and brain tissues [2].


  1. Ischemia induces a translocation of the splicing factor tra2-beta 1 and changes alternative splicing patterns in the brain. Daoud, R., Mies, G., Smialowska, A., Oláh, L., Hossmann, K.A., Stamm, S. J. Neurosci. (2002) [Pubmed]
  2. Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2. Segade, F., Hurlé, B., Claudio, E., Ramos, S., Lazo, P.S. FEBS Lett. (1996) [Pubmed]
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