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Gene Review

Prmt7  -  protein arginine N-methyltransferase 7

Mus musculus

Synonyms: 4933402B05Rik, BC006705, Histone-arginine N-methyltransferase PRMT7, Kiaa1933, Protein arginine N-methyltransferase 7
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High impact information on Prmt7

  • Gene expression analysis indicated that susceptibility alleles at the DOXNPH locus are associated with blunted expression of protein arginine methyltransferase 7 (Prmt7) on chromosome 8, a protein previously implicated in cellular sensitivity to chemotherapeutic agents (lod = 12.4, P = 0.0001) [1].


  1. A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse. Zheng, Z., Schmidt-Ott, K.M., Chua, S., Foster, K.A., Frankel, R.Z., Pavlidis, P., Barasch, J., D'Agati, V.D., Gharavi, A.G. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
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