The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

PRMT7  -  protein arginine methyltransferase 7

Homo sapiens

Synonyms: FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Protein arginine N-methyltransferase 7
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of PRMT7


High impact information on PRMT7


Biological context of PRMT7


Anatomical context of PRMT7


Associations of PRMT7 with chemical compounds


Regulatory relationships of PRMT7

  • In vitro studies demonstrate that CTCFL stimulates the histone-methyltransferase activity of PRMT7 via interactions with both histones and PRMT7 [3].

Other interactions of PRMT7

  • GST fusions of PRMT4 or PRMT7 were unable to methylate the full-length protein or its degradation products [4].


  1. PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine. Lee, J.H., Cook, J.R., Yang, Z.H., Mirochnitchenko, O., Gunderson, S.I., Felix, A.M., Herth, N., Hoffmann, R., Pestka, S. J. Biol. Chem. (2005) [Pubmed]
  2. PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity. Miranda, T.B., Miranda, M., Frankel, A., Clarke, S. J. Biol. Chem. (2004) [Pubmed]
  3. The Testis-Specific Factor CTCFL Cooperates with the Protein Methyltransferase PRMT7 in H19 Imprinting Control Region Methylation. Jelinic, P., Stehle, J.C., Shaw, P. PLoS Biol. (2006) [Pubmed]
  4. Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a. Miranda, T.B., Webb, K.J., Edberg, D.D., Reeves, R., Clarke, S. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
WikiGenes - Universities