Gene Review:
Thse - t haplotype specific elements
Mus musculus
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Disease relevance of Thse
- The complete nucleotide sequence of one 7.8-kb TSE reveals significant homology to the ETn (a major transcript in the early embryo of the mouse), and some homologies to intracisternal A-particles and the mammary tumor virus env gene [1].
High impact information on Thse
- The TSEs exist as submegabase-long clusters of tandem repeats localized in the Tla region of the major histocompatibility complex of all t haplotype chromosomes examined [1].
- Dramatic quantitative differences of TSEs uniquely distinguish every independent t haplotype from any other [1].
References
- Submegabase clusters of unstable tandem repeats unique to the Tla region of mouse t haplotypes. Uehara, H., Ebersole, T., Bennett, D., Artzt, K. Genetics (1990) [Pubmed]
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