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Gene Review

Rbm27  -  RNA binding motif protein 27

Mus musculus

Synonyms: A730010I06, AI043120, Kiaa1311, Peri-implantation stem cell protein 1, Psc1, ...
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High impact information on Rbm27

  • We coupled an in vitro model of primitive ectoderm formation (the transition of embryonic stem cells to early primitive ectoderm-like (EPL) cells) with ddPCR-based techniques to identify three novel genes, Psc1, CRTR-1 and PRCE, that were expressed differently during pluripotent cell progression [1].
  • The Psc1 sequence includes an RS domain and an RNA recognition motif (RRM), and a sequential arrangement of protein motifs that has not been demonstrated for other RS domain proteins [2].


  1. Transient pluripotent cell populations during primitive ectoderm formation: correlation of in vivo and in vitro pluripotent cell development. Pelton, T.A., Sharma, S., Schulz, T.C., Rathjen, J., Rathjen, P.D. J. Cell. Sci. (2002) [Pubmed]
  2. A family of RS domain proteins with novel subcellular localization and trafficking. Kavanagh, S.J., Schulz, T.C., Davey, P., Claudianos, C., Russell, C., Rathjen, P.D. Nucleic Acids Res. (2005) [Pubmed]
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