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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

FLRT2  -  fibronectin leucine rich transmembrane...

Homo sapiens

Synonyms: Fibronectin-like domain-containing leucine-rich transmembrane protein 2, KIAA0405, Leucine-rich repeat transmembrane protein FLRT2, UNQ232/PRO265
 
 
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High impact information on FLRT2

  • In gain- and loss-of function experiments, FLRT3 and FLRT2 phenocopy FGF signalling in Xenopus laevis [1].
  • When expressed in SF9 and COS-1 cells, FLRT1 and FLRT2 migrate as 90- and 85-kDa proteins, respectively, and both are glycosylated [2].
 

Anatomical context of FLRT2

References

  1. The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling. Böttcher, R.T., Pollet, N., Delius, H., Niehrs, C. Nat. Cell Biol. (2004) [Pubmed]
  2. Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins. Lacy, S.E., Bönnemann, C.G., Buzney, E.A., Kunkel, L.M. Genomics (1999) [Pubmed]
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