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Gene Review

FRA5C  -  fragile site, aphidicolin type, common,...

Homo sapiens

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High impact information on FRA5C

  • In one cell line, where comparative genomic hybridization showed DNA copy number gain confined to the region 5q31, we detected by FISH high-level amplification of the SMAD5 gene located within the fragile site FRA5C [1].

Biological context of FRA5C


  1. SMAD5 gene expression, rearrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinoma. Zimonjic, D.B., Durkin, M.E., Keck-Waggoner, C.L., Park, S.W., Thorgeirsson, S.S., Popescu, N.C. Neoplasia (2003) [Pubmed]
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