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Gene Review

Gos28  -  Golgi SNARE, 28 kDa

Drosophila melanogaster

Synonyms: CG7700, Dmel\CG7700, FSG28, GOS28, Golgi SNAP receptor complex member 1, ...
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High impact information on Gos28

  • NSF/alpha-SNAP catalyze the binding of GATE-16 to GOS-28, a Golgi v-SNARE, in a manner that requires ATP but not ATP hydrolysis [1].
  • GATE-16 is essential for NSF-driven Golgi reassembly and precludes GOS-28 from binding to its cognate t-SNARE, syntaxin-5 [1].


  1. Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion. Muller, J.M., Shorter, J., Newman, R., Deinhardt, K., Sagiv, Y., Elazar, Z., Warren, G., Shima, D.T. J. Cell Biol. (2002) [Pubmed]
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