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Gene Review:

zfs1 - zinc finger protein

Schizosaccharomyces pombe 972h-

Beltraminelli, N. et al., Goldar, M.M. et al., Kanoh, J. et al.

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High impact information on zfs1

Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway [1].
We conclude that zfs1 function is required to prevent septum formation and exit from mitosis if the mitotic spindle is not assembled [2].
The genetic interactions of zfs1 with genes regulating septum formation suggest that it may be a modulator of the signal transduction network controlling the onset of septum formation and exit from mitosis [2].
Those phenotypes were opposite to the phenotypes observed in a zfs1 disruptant, and quite different from the ones in a moc1 disruptant [3].

References

Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway. Kanoh, J., Sugimoto, A., Yamamoto, M. Mol. Biol. Cell (1995) [Pubmed]
The S. pombe zfs1 gene is required to prevent septation if mitotic progression is inhibited. Beltraminelli, N., Murone, M., Simanis, V. J. Cell. Sci. (1999) [Pubmed]
Moc3, a novel Zn finger type protein involved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe. Goldar, M.M., Jeong, H.T., Tanaka, K., Matsuda, H., Kawamukai, M. Curr. Genet. (2005) [Pubmed]

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