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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Bcmd2  -  B cell maturation defect 2

Mus musculus

Synonyms: Bcmd-2
 
 
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Disease relevance of Bcmd2

 

High impact information on Bcmd2

  • We have now mapped a second QTL controlling the B-cell deficiency, Bcmd-2, to Chr 4 [1].
 

Biological context of Bcmd2

  • The Bcmd-1 locus is the major regulator of B-cell homeostasis, while Bcmd-2 is the minor regulator, and their effects are additive, as shown by splenic B-cells analysis in these congenic strains [1].

References

  1. Genetic studies of B-lymphocyte deficiency and mastocytosis in strain A/WySnJ mice. Clise-Dwyer, K., Amanna, I.J., Duzeski, J.L., Nashold, F.E., Hayes, C.E. Immunogenetics (2001) [Pubmed]
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