The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

LSM14A  -  LSM14A, SCD6 homolog A (S. cerevisiae)

Homo sapiens

Synonyms: AlphaSNBP, C19orf13, DKFZP434D1335, FAM61A, Protein FAM61A, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on LSM14A

  • RAP55 localized to cytoplasmic foci in Xenopus oocytes and the processing bodies (P-bodies) in cultured human cells: in the latter cells, RAP55 is an essential constituent of the P-bodies [1].
  • After cells were subjected to arsenite-induced stress, RAP55 was detected in TIA-containing stress granules [2].
  • The second RGG domain was necessary and sufficient for stress granule localization. siRNA-mediated knock-down of RAP55 resulted in loss of P-bodies, suggesting that RAP55 acts prior to the 5'-decapping step in mRNA degradation [2].
 

Anatomical context of LSM14A

References

  1. RAP55, a Cytoplasmic mRNP Component, Represses Translation in Xenopus Oocytes. Tanaka, K.J., Ogawa, K., Takagi, M., Imamoto, N., Matsumoto, K., Tsujimoto, M. J. Biol. Chem. (2006) [Pubmed]
  2. RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules. Yang, W.H., Yu, J.H., Gulick, T., Bloch, K.D., Bloch, D.B. RNA (2006) [Pubmed]
 
WikiGenes - Universities