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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

FGFR1OP2  -  FGFR1 oncogene partner 2

Homo sapiens

Synonyms: DKFZp564O1863, HSPC123, HSPC123-like, WIT3.0
 
 
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High impact information on FGFR1OP2

  • Subsequent analysis led to the identification of a fusion of the FGFR1OP2 gene to the FGFR1 gene [1].
  • Using 5'-RACE PCR, we identified part of a novel gene, FGFR1OP2, at chromosome band 12p11 that was fused to exon 9 of FGFR1.FGFR1OP2 is predicted to be translated into an evolutionarily conserved protein containing coiled-coil domains but no other recognizable motifs [2].
 

Other interactions of FGFR1OP2

  • Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome [2].

References

  1. Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia. Gu, T.L., Goss, V.L., Reeves, C., Popova, L., Nardone, J., Macneill, J., Walters, D.K., Wang, Y., Rush, J., Comb, M.J., Druker, B.J., Polakiewicz, R.D. Blood (2006) [Pubmed]
  2. Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome. Grand, E.K., Grand, F.H., Chase, A.J., Ross, F.M., Corcoran, M.M., Oscier, D.G., Cross, N.C. Genes Chromosomes Cancer (2004) [Pubmed]
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