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Gene Review

traA  -  conjugal transfer pilin subunit TraA

Escherichia coli

 
 
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Disease relevance of traA

 

High impact information on traA

  • Interaction between the F plasmid TraA (F-pilin) and TraQ proteins [2].
  • Attempts to isolate an F-pilin-TraQ complex from E. coli were unsuccessful, suggesting that the interaction between the two is normally transient, as expected from previous studies of the kinetics of TraA membrane insertion and processing to F-pilin [2].
  • A second fusion gene encoded the TraA leader peptide and the first 51 amino acids of F-pilin itself fused to PhoA (TraA'-'PhoA-102 polypeptide) [3].
  • A traA null mutant of plasmid R1-16, which lacks the functional gene encoding the major pilus protein pilin, showed distinctly reduced stress responses [4].

References

 
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