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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

IGHV1-2  -  immunoglobulin heavy variable 1-2

Homo sapiens

Synonyms: IGHV12, V35
 
 
 
 
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High impact information on IGHV1-2

  • The results show that all hybridoma cells analyzed rearranged exclusively the IGHV1-2 gene, in contrast with naive spleen B cells that used three out of the five IGHV genes present in the transgene [1].

References

  1. Rearrangement of only one human IGHV gene is sufficient to generate a wide repertoire of antigen specific antibody responses in transgenic mice. Suárez, E., Magadán, S., Sanjuán, I., Valladares, M., Molina, A., Gambón, F., Díaz-Espada, F., González-Fernández, A. Mol. Immunol. (2006) [Pubmed]
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