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Gene Review

UGT1A6  -  UDP glucuronosyltransferase 1 family,...

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High impact information on UGT1A4

  • LTG N2-glucuronidation by recombinant UGT1A4 exhibited Michaelis-Menten kinetics, with a Km of 1558 microM [1].


  1. In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction. Rowland, A., Elliot, D.J., Williams, J.A., Mackenzie, P.I., Dickinson, R.G., Miners, J.O. Drug Metab. Dispos. (2006) [Pubmed]
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