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Gene Review: 

mc5rb  -  melanocortin 5b receptor

Danio rerio

Synonyms: SO:0000704, mc5br, mc5ra, zMC5b, zgc:194217
 
 
 
 
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High impact information on mc5rb

  • The zMC4, zMC5a, and zMC5b receptors share 70-71% overall amino acid identity with the respective human orthologues and over 90% in three TM regions believed to be most important for ligand binding [1].
  • All three genes were expressed in the brain, eye, ovaries and gastrointestinal tract, whereas the zMC5b receptor was also found in the heart, as determined by RT-PCR [1].

References

  1. One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology. Ringholm, A., Fredriksson, R., Poliakova, N., Yan, Y.L., Postlethwait, J.H., Larhammar, D., Schiöth, H.B. J. Neurochem. (2002) [Pubmed]
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