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Gene Review

mc5ra  -  melanocortin 5a receptor

Danio rerio

Synonyms: SO:0000704, mc5ar, mc5rb, zMC5a
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High impact information on mc5ra

  • The zMC4, zMC5a, and zMC5b receptors share 70-71% overall amino acid identity with the respective human orthologues and over 90% in three TM regions believed to be most important for ligand binding [1].


  1. One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology. Ringholm, A., Fredriksson, R., Poliakova, N., Yan, Y.L., Postlethwait, J.H., Larhammar, D., Schiöth, H.B. J. Neurochem. (2002) [Pubmed]
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