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Cnot6  -  CCR4-NOT transcription complex, subunit 6

Rattus norvegicus

Synonyms: CCR4, CCR4 carbon catabolite repression 4-like, CCR4-NOT transcription complex subunit 6, Carbon catabolite repressor protein 4 homolog, Ccr4, ...
 
 
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High impact information on RGD1310783

  • Our data indicate that instead of Th2 cells, airway epithelial cells expressing CCR4 might be the principal targets for MDC and TARC released from alveolar macrophages during cigarette smoke-induced airway inflammation [1].
  • CXCR3 and CCR4 thus appear to be available as markers for Th1/Th2 subsets in the synovia of AA rats [2].

References

  1. Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation. Ritter, M., Göggel, R., Chaudhary, N., Wiedenmann, A., Jung, B., Weith, A., Seither, P. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
  2. Effect of the resection of the sciatic nerve on the Th1/Th2 balance in the synovia of the ankle joint of adjuvant arthritic rats. Wu, Z., Toh, K., Nagata, K., Kukita, T., Iijima, T. Histochem. Cell Biol. (2004) [Pubmed]
 
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