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Gene Review:

xcpR - general secretion pathway protein E

Acinetobacter sp. ADP1

Parche, S. et al., Ratajczak, A. et al.

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Disease relevance of xcpR

Identification and characterization of xcpR encoding a subunit of the general secretory pathway necessary for dodecane degradation in Acinetobacter calcoaceticus ADP1 [1].

High impact information on xcpR

In Acinetobacter sp. strain ADP1, alkane degradation depends on at least five essential genes. rubAB and xcpR are constitutively transcribed [2].
Insertional inactivation of xcpR in A. calcoaceticus ADP1 by transcriptional fusion to lacZ abolishes secretion of lipase and esterase and leads to lack of growth on dodecane and slower growth on hexadecane [1].

References

Identification and characterization of xcpR encoding a subunit of the general secretory pathway necessary for dodecane degradation in Acinetobacter calcoaceticus ADP1. Parche, S., Geissdörfer, W., Hillen, W. J. Bacteriol. (1997) [Pubmed]
Expression of alkane hydroxylase from Acinetobacter sp. Strain ADP1 is induced by a broad range of n-alkanes and requires the transcriptional activator AlkR. Ratajczak, A., Geissdörfer, W., Hillen, W. J. Bacteriol. (1998) [Pubmed]

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