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SAP30BP  -  SAP30 binding protein

Homo sapiens

Synonyms: HCNGP, HTRG, HTRP, SAP30-binding protein, Transcriptional regulator protein HCNGP
 
 
 
 
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High impact information on SAP30BP

  • The results of a yeast two-hybrid experiment indicated that HTRP is indeed involved in the interaction with the SAP (mSin3-associate polypeptide) complex via SAP30 [1].
  • The localization of HTRP expressed as a fusion polypeptide with a fluorescent protein in HeLa cells was confirmed to be the nucleus [1].
 

Biological context of SAP30BP

  • The interaction of HTRP with SAP30 in its conserved domain implies that this protein family, as the products of immediate-early genes, comprise functional molecules involved in the transcriptional regulation of cells, which might be related to the inhibition of some cell survival genes [1].

References

  1. HTRP--an immediate-early gene product induced by HSV1 infection in human embryo fibroblasts, is involved in cellular co-repressors. Li, J.F., Liu, L.D., Ma, S.H., Che, Y.C., Wang, L.C., Dong, C.H., Zhao, H.L., Liao, Y., Li, Q.H. J. Biochem. (2004) [Pubmed]
 
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