MeSH Review:
Cell Survival
- Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. McGill, G.G., Horstmann, M., Widlund, H.R., Du, J., Motyckova, G., Nishimura, E.K., Lin, Y.L., Ramaswamy, S., Avery, W., Ding, H.F., Jordan, S.A., Jackson, I.J., Korsmeyer, S.J., Golub, T.R., Fisher, D.E. Cell (2002)
- Homologous plant and bacterial proteins chaperone oligomeric protein assembly. Hemmingsen, S.M., Woolford, C., van der Vies, S.M., Tilly, K., Dennis, D.T., Georgopoulos, C.P., Hendrix, R.W., Ellis, R.J. Nature (1988)
- Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Ling, K., Doughman, R.L., Firestone, A.J., Bunce, M.W., Anderson, R.A. Nature (2002)
- p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas. Singh, B., Reddy, P.G., Goberdhan, A., Walsh, C., Dao, S., Ngai, I., Chou, T.C., O-Charoenrat, P., Levine, A.J., Rao, P.H., Stoffel, A. Genes Dev. (2002)
- Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. Muraoka, R.S., Dumont, N., Ritter, C.A., Dugger, T.C., Brantley, D.M., Chen, J., Easterly, E., Roebuck, L.R., Ryan, S., Gotwals, P.J., Koteliansky, V., Arteaga, C.L. J. Clin. Invest. (2002)
- PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. Baki, L., Shioi, J., Wen, P., Shao, Z., Schwarzman, A., Gama-Sosa, M., Neve, R., Robakis, N.K. EMBO J. (2004)
- Dystrophin mutations predict cellular susceptibility to oxidative stress. Disatnik, M.H., Chamberlain, J.S., Rando, T.A. Muscle Nerve (2000)
- Regulation of lymphocyte survival by the bcl-2 gene family. Cory, S. Annu. Rev. Immunol. (1995)
- The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Chang, L., Kamata, H., Solinas, G., Luo, J.L., Maeda, S., Venuprasad, K., Liu, Y.C., Karin, M. Cell (2006)
- The enigmatic role of Sir2 in aging. Kennedy, B.K., Smith, E.D., Kaeberlein, M. Cell (2005)
- IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Hu, M.C., Lee, D.F., Xia, W., Golfman, L.S., Ou-Yang, F., Yang, J.Y., Zou, Y., Bao, S., Hanada, N., Saso, H., Kobayashi, R., Hung, M.C. Cell (2004)
- A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Jan, Y., Matter, M., Pai, J.T., Chen, Y.L., Pilch, J., Komatsu, M., Ong, E., Fukuda, M., Ruoslahti, E. Cell (2004)
- Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas. Ohd, J.F., Nielsen, C.K., Campbell, J., Landberg, G., Löfberg, H., Sjölander, A. Gastroenterology (2003)
- Inhibition of nonlysosomal calcium-dependent proteolysis by glycine during anoxic injury of rat hepatocytes. Nichols, J.C., Bronk, S.F., Mellgren, R.L., Gores, G.J. Gastroenterology (1994)
- Integrin alphav-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen. Bao, W., Strömblad, S. J. Cell Biol. (2004)
- ALADINI482S causes selective failure of nuclear protein import and hypersensitivity to oxidative stress in triple A syndrome. Hirano, M., Furiya, Y., Asai, H., Yasui, A., Ueno, S. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Pattingre, S., Tassa, A., Qu, X., Garuti, R., Liang, X.H., Mizushima, N., Packer, M., Schneider, M.D., Levine, B. Cell (2005)
- Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Datta, S.R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., Greenberg, M.E. Cell (1997)
- The NUP1 gene encodes an essential component of the yeast nuclear pore complex. Davis, L.I., Fink, G.R. Cell (1990)
- RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C. Mann, C., Buhler, J.M., Treich, I., Sentenac, A. Cell (1987)
- Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription. Ogas, J., Andrews, B.J., Herskowitz, I. Cell (1991)
- Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Hirota, H., Chen, J., Betz, U.A., Rajewsky, K., Gu, Y., Ross, J., Müller, W., Chien, K.R. Cell (1999)
- Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Lee, M.J., Thangada, S., Claffey, K.P., Ancellin, N., Liu, C.H., Kluk, M., Volpi, M., Sha'afi, R.I., Hla, T. Cell (1999)
- Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Schipani, E., Ryan, H.E., Didrickson, S., Kobayashi, T., Knight, M., Johnson, R.S. Genes Dev. (2001)
- Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors. Sutton, V.R., Wowk, M.E., Cancilla, M., Trapani, J.A. Immunity (2003)
- Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Stüber, E., Neurath, M., Calderhead, D., Fell, H.P., Strober, W. Immunity (1995)
- Microtubule stabilization by taxol inhibits initiation of DNA synthesis by thrombin and by epidermal growth factor. Crossin, K.L., Carney, D.H. Cell (1981)
- Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand. Mellon, I., Hanawalt, P.C. Nature (1989)
- Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Griffin, L.D., Gong, W., Verot, L., Mellon, S.H. Nat. Med. (2004)
- 5-bromo-2'-deoxyuridine blocks myogenesis by extinguishing expression of MyoD1. Tapscott, S.J., Lassar, A.B., Davis, R.L., Weintraub, H. Science (1989)
- Requirement for BDNF in activity-dependent survival of cortical neurons. Ghosh, A., Carnahan, J., Greenberg, M.E. Science (1994)
- A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction. Park, Y.C., Ye, H., Hsia, C., Segal, D., Rich, R.L., Liou, H.C., Myszka, D.G., Wu, H. Cell (2000)
- Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53. Parant, J., Chavez-Reyes, A., Little, N.A., Yan, W., Reinke, V., Jochemsen, A.G., Lozano, G. Nat. Genet. (2001)
- Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts. Hess, P., Pihan, G., Sawyers, C.L., Flavell, R.A., Davis, R.J. Nat. Genet. (2002)
- The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Wang, S.L., Hawkins, C.J., Yoo, S.J., Müller, H.A., Hay, B.A. Cell (1999)
- The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Huang, M., Zhou, Z., Elledge, S.J. Cell (1998)
- CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers. Huntington, N.D., Xu, Y., Puthalakath, H., Light, A., Willis, S.N., Strasser, A., Tarlinton, D.M. Nat. Immunol. (2006)
- Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A. J. Natl. Cancer Inst. (1991)
- Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death. French, L.E., Wohlwend, A., Sappino, A.P., Tschopp, J., Schifferli, J.A. J. Clin. Invest. (1994)
- Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver. Joseph, B., Malhi, H., Bhargava, K.K., Palestro, C.J., McCuskey, R.S., Gupta, S. Gastroenterology (2002)
- Yeast NOP2 encodes an essential nucleolar protein with homology to a human proliferation marker. de Beus, E., Brockenbrough, J.S., Hong, B., Aris, J.P. J. Cell Biol. (1994)